The Serum Institute of India was founded in 1966 and is the largest manufacturer of vaccines by number of doses produced and sold globally (more than 1.5 billion doses). An estimated 65 percent of the children in the world receive at least one vaccine manufactured by the Institute. Its facilities operate under current Good Manufacturing Practice (cGMP) guidelines, have been accredited by the World Health Organization (WHO) and comply with US Food and Drug Administration (FDA) and UK Medicines and Healthcare products Regulatory Agency (MHRA) requirements for quality, purity, efficacy and safety.